"TO THRIVE AS A FIELD, DIGITAL MEDICINE REQUIRES AN UNPRECEDENTED LEVEL OF INTERDISCIPLINARY COLLABORATION. FROM REGULATORS TO WHITE-HAT HACKERS, ETHICISTS TO ENGINEERS, AND CLINICIANS TO CITIZEN SCIENTISTS, NEW COOPERATIVE NETWORKS MUST EMERGE TO ENSURE THAT DIGITAL MEDICINE REALIZES ITS FULL POTENTIAL TO IMPROVE HUMAN HEALTH." (DIGITAL MEDICINE SOCIETY)
Returning to Pfizer in Cambridge, the Digital Implementation Forum focuses on ways for life sciences to take advantage of new opportunities within digital health and digital measurement; as well as how these new data can supplement existing collection strategies to drive research forward. Be a part of the movement to get these validated digital measures and digital health tools (DHTs) into the hands of patients, their physicians and caregivers.

Join 30+ speakers, 150 senior-level pharma, clinical trials, technology and digital health executives this November 5, 2025 at Pfizer in Cambridge to learn, network, develop and improve the way digital health measurement tools are being created, validated, scaled and deployed in life sciences to improve data quality, improve patient experience & accelerate drug development and patient care.

For 2025, the event will be co-created and led by both Pfizer & Johnson & Johnson Innovative Medicine. This collaborative approach is exciting for the field and shows the true nature of this event from its inception; a place for all at the table!
Location
Pfizer Innovation Research (PfIRe Lab)
1 Portland St
Cambridge, MA 02139
Date & Time
November 5, 2025
9:00am - 5:30pm
2025 CORE THEMES

1. Preclinical to Clinical Translation of Digital Measures

• What sort of value can be delivered with the integration of digital tools from Phase 0 to Phase 4 and beyond; and how much measurement is too much? 
• How to retain investment in preclinical digital measures and protocols throughout the entire clinical study lifecycle
 
2. The Importance of Winning Patient Engagement Strategies when Developing Novel Digital Measures


• How to engage with patients directly about measures that matter to them
• How to engage with sites to determine existing workflows and best operationalize deployment of additional digital resources
• How to convince project teams that it is a good idea to implement more digital into study protocols

3. How to make Digital Health Products Successful & Establish Valuable Digital Measures for use in Health Care

• The Importance of Monitoring Digital Data in Clinical Trials
• Digital disease management and key learnings from clinical trials
• From the perspective of HCPs, how digital can improve the patient care scenario without being overly burdensome 

4. Regulatory - Managing Expectations, Key Learnings and getting to the Finish Line

The latest regulatory approval pathways & advances for digital measures: the state of the space
• Stakeholder collaborations leading progress for Digital Therapeutics
• Regulatory experts discuss hot topics: AI-driven decision support, digital endpoint validation, decentralized oversight, and the evolving role of real-world data.


2025 Speakers and Advisors
Carrie Northcott
Head of Digital Medicine and Translational Imaging
(Pfizer Chair)
PFIZER
Tim McCarthy
VP, Head of CT&B
(Pfizer Chair)
PFIZER
Charmaine Demanuele
VP, Data Science & Digital Health
(J&J Chair)
J&J Innovative Medicine

Phil Murphy
Head of Imaging & Digital Health
(J&J Chair)
J&J Innovative Medicine
Raúl Torres
Associate Director, Data Science
TAKEDA
Bola Grace
Sr. Director, Digital Health
GSK
Bhaskar Dutta
Head of Digital Health & Med Affairs Technologies
ALEXION
Lorcan Walsh
Head of Digital Endpoint Capability Centre
NOVARTIS
Anthony Costello
CEO
MEDIDATA
David Benshoof Klein
CEO
CLICK THERAPEUTICS
Bhavna Adhin
Director, Clinical Informatics
PFIZER
Mark Morris
Director, Digital Clinical Measurement
J&J Innovative Medicine
Francesca Cormack
Chief Scientist
CAMBRIDGE COGNITION
Chang-Ning Liu
Lead of Animal Models & Imaging
PFIZER
Rebecca Shilling
Clinical Development Asset Lead
ARGENX
Kate Lyden
Director of Science
VIVOSENSE
Musaddiq Khan
VP, Customer Value Digital Outcomes and TA Strategy
MEDABLE
Meenakshi Chatterjee
Sr. Principal Scientist, Data Science & Digital Health
J&J Innovative Medicine
Isik Karahanoglu
Director, Early Clinical Development, Digital Sciences
PFIZER
Bryan Fry
Acoustic Data Scientist
PFIZER
Brett Hauber
Senior Director, Patient Preference Expert
PFIZER
Matteo Lai
CEO
Empatica
Kara Chappie
Director
PFIZER
Srinivasan Vairavan
Director, Digital and AI Biomarkers
J&J Innovative Medicine
Ilan Wapinski
Head of In Silico Research & CMC
SANOFI
Sheraz Khan
Group Lead Generative AI
PFIZER
Sarah Ernst
Head of Clinical Innovation Strategy and Implementation
SANOFI
Andrew Elias
Director, Global Regulatory Affairs
JOHNSON & JOHNSON INNOVATIVE MEDICINE
Jacqueline Thong
General Manager, US
DEEP MEASURES
Jared Worful
Head of Digital Health Technology & Real-World Science
BAYER
Daniel R. Frisch, MD
Director, Electrophysiology Section
THOMAS JEFFERSON UNIVERSITY HOSPITAL
Szczepan Baran
Principal
BaRAN CAFE
Nader Naghavi
Senior Manager, Digital Biomarkers
REGENERON
Christopher Regan
Executive Director, Safety & Exploratory Pharmacology
MERCK
Megan Gross
Head of Project Delivery & Research
AICURE
Agenda: November 5, 2025
8:00 AM

Registration, Coffee and Conversation
Conference registration open with continental breakfast and coffee served
9:00 AM

Opening Remarks from Conference Chairs

Carrie Northcott, Head of Digital Medicine and Translational Imaging, Pfizer (Pfizer Chair)
Tim McCarthy, VP, Head of CT&B, Pfizer (Pfizer Chair)
Charmaine Demanuele, VP, Data Science & Digital Health, Johnson & Johnson Innovative Medicine (J&J Chair)
Phil Murphy, Head of Imaging & Digital Health, Johnson & Johnson Innovative Medicine (J&J Chair)
9:10 AM

Preclinical to Clinical Translation of Digital Measures

Chang-Ning Liu, Lead of Animal Models & Imaging, Pfizer
Ilan Wapinski, Head of In Silico Research & CMC, Sanofi
Szczepan Baran, Principal, Baran Cafe
Charmaine Demanuele, VP, Data Science & Digital Health, Johnson & Johnson Innovative Medicine 
9:35 AM

Digital Applications for Experimental Medicine Inflammatory Challenge Studies

Meenakshi Chatterjee, Senior Principal Scientist, Data Science & Digital Health, Johnson & Johnson Innovative Medicine
9:50 AM

Unfolding the Value Proposition for Accelerometry-measured Sleep in people with Narcolepsy type 1
Discuss results from phase 0 to phase 3 to demonstrate how Takeda gained and retained investment in these digital endpoints across 5 years. The talk will be anchored on some scientific results.

Raúl Torres, Associate Director, Data Science, Takeda
10:05 AM

Digital Cognitive Assessments: Supporting the Translation of Basic Science Insights to Clinical Trials and Clinical Practice

Francesca Cormack, Chief Scientist, Cambridge Cognition
10:25 AM

NETWORKING COFFEE BREAK

10:50 AM

The Importance of Winning Patient Engagement Strategies when Developing Novel Digital Measures

Phil Murphy, Head of Imaging and Digital Health, Johnson & Johnson (Session Chair)
10:50 aM

Next-Gen Medical Affairs: Digital Health for Rare Diseases

Bhaskar Dutta, Head of Digital Health & Medical Affairs Technologies, Alexion
11:05 aM

A New Era for Clinical Trials: Software-Enhanced Drug(TM) Treatments

As the pharmaceutical industry evolves toward more holistic, patient-centered care models, Software-Enhanced (SE) Drugs are emerging as a powerful strategy to differentiate products, improve outcomes, and extend therapeutic value. In this joint session, Medidata and Click Therapeutics will introduce the core concept of Software-Enhanced Drugs and explain the impact on clinical trials.

Anthony Costello, CEO, Medidata Solutions
David Benshoof Klein, CEO, Click Therapeutics
11:25 aM

Ensuring Universal Accuracy: Algorithm Development and Device-Agnostic Validation for Nocturnal Scratch and Sleep

Isik Karahanoglu, Director, Early Clinical Development, Digital Sciences, Pfizer
11:40 AM

PANEL DISCUSSION: The Importance of Winning Patient Engagement Strategies when Developing Novel Digital Measures

Brett Hauber, Senior Director, Patient Preference Expert, Pfizer
Musaddiq Khan, VP, Customer Value, Digital Outcomes and TA Strategy, Medable
Nader Naghavi, Digital Biomarkers Lead, Regeneron
Tim McCarthy, VP, Head of CT&B, Pfizer
Moderated by: Phil Murphy, Head of Imaging and Digital Health, Johnson & Johnson

12:05 PM

NETWORKING LUNCHEON

1:05 PM

Can we use Digital Measures to blend Clinical Care and Clinical Trials? A template for Parkinson's

Matteo Lai, CEO, Empatica
1:15 PM

How to make Digital Health Products Successful & Establish Valuable Digital Measures for use in Health Care

Kara Chappie, Director, Pfizer (Session Chair)
1:15 PM

PANEL DISCUSSION: How to make Digital Health Products Successful & Establish Valuable Digital Measures for use in Health Care

Srinivasan Vairavan, Director, Digital and AI Biomarkers, Johnson & Johnson Innovative Medicine
Lorcan Walsh, Head of Digital Endpoint Capability Centre, Novartis
Sarah Ernst, Head of Clinical Innovation Strategy and Implementation, Sanofi
Moderated by: Kara Chappie, Director, Pfizer
1:40 PM

The Importance of Monitoring Digital Data in Clinical Trials

Bhavna Adhin, Director, Clinical Informatics, Pfizer
Bryan Fry, Acoustic Data Scientist, Pfizer

1:55 PM

Development of Heart Rate Variability for Inflammatory Bowel Disease Clinical Management and Clinical Trials

Mark Morris, Director, Digital Clinical Measurement, Johnson & Johnson Innovative Medicine

2:10 PM

From the Cardiology Clinic to a Trial: A Guide to Implementing Remote Monitoring ECG Data

Daniel R. Frisch, MD, FHRS, FACC, Associate Professor of Medicine, Director, Electrophysiology Section, Bruce & Robbi Toll Heart and Vascular Institute, Thomas Jefferson University Hospital

2:30 PM

NETWORKING COFFEE AND REFRESHMENT BREAK
3:00 PM

Managing Regulatory Expectations - Collaborations, Key Learnings and getting to the Finish Line

Carrie Northcott, Head of Digital Medicine and Translational Imaging, Pfizer (Session Chair)
3:00 PM

Toward a Comprehensive Digital Endpoint Strategy for Congenital Myasthenic Syndromes: Linking In-Clinic Performance, Real-World Function, and Regulatory Readiness

Kate Lyden, Chief Science Officer, Vivosense
Rebecca Shilling, Clinical Development Asset Lead, argenx
3:20 PM

PANEL DISCUSSION: How Content Consolidation from Public-Private Partnerships Accelerate Regulatory-Ready Digital Endpoints

Jared Worful, Head of Digital Health Technology & Real-World Science, Bayer
Carrie Northcott, Head of Digital Medicine and Translational Imaging, Pfizer
Jacqueline Thong, General Manager, US, DEEP Measures
3:40 PM

PANEL DISCUSSION: Managing Regulatory Expectations - Collaborations, Key Learnings and getting to the Finish Line

Sheraz Khan, Group Lead, Generative AI, Pfizer
Bola Grace, Sr. Director, Digital Health, GSK
Andrew Elias, Director, Global Regulatory Affairs, Johnson & Johnson Innovative Medicine
Moderated by: Carrie Northcott, Head of Digital Medicine and Translational Imaging, Pfizer
4:00 - 5:30 PM

NETWORKING RECEPTION


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Location
Pfizer Innovation Research (PfIRe) Lab 
Cambridge, MA
The PfIRe Lab is a highly instrumented clinical research facility located in Cambridge, Massachusetts. Here, researchers use cutting-edge wearable and environmental sensors to develop and validate novel, patient-centric clinical endpoints, thereby potentially enabling a better understanding of a patient’s disease state and response to therapy.

Pfizer’s Digital Medicine & Translational Imaging Team recently unveiled this industry-leading facility in Cambridge, Massachusetts, designed to rapidly evaluate and validate novel technologies for potential use in clinical trials. In the PfIRe Lab, a multidisciplinary team of clinicians and researchers utilize state-of-the-art motion capture technologies, coupled with environmental and wearable sensors to develop new patient-centric clinical trial endpoints, enabling measures of physical function and activity outside of the traditional hospital and clinical settings.
 Join us at the 
Digital Implementation Summit 2025!
The Premiere Event focused on Digital Measurements Developed for Clinical Research to ultimate Clinical Utility; for the Benefit of Patients and their Healthcare Providers

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